Accéder directement au contenu Accéder directement à la navigation
Article dans une revue

Rye polyphenols and the metabolism of n-3 fatty acids in rats: a dose dependent fatty fish-like effect

Abstract : As long-chain fatty acids (LCFA) of the n-3 series are critically important for human health, fish consumption has considerably increased in recent decades, resulting in overfishing to respond to the worldwide demand, to an extent that is not sustainable for consumers' health, fisheries economy, and marine ecology. In a recent study, it has been shown that whole rye (WR) consumption improves blood and liver n-3 LCFA levels and gut microbiota composition in rats compared to refined rye. The present work demonstrates that specific colonic polyphenol metabolites may dose dependently stimulate the synthesis of n-3 LCFA, possibly through their microbial and hepatic metabolites in rats. The intake of plant n-3 alpha-linolenic acid and WR results in a sort of fatty fish-like effect, demonstrating that the n-3 LCFA levels in blood and tissues could be increased without eating marine foods, and therefore without promoting unsustainable overfishing, and without damaging marine ecology.
Type de document :
Article dans une revue
Liste complète des métadonnées

Littérature citée [29 références]  Voir  Masquer  Télécharger

https://hal.univ-grenoble-alpes.fr/hal-01928613
Contributeur : Sarah Hamant <>
Soumis le : mercredi 17 juillet 2019 - 15:59:52
Dernière modification le : mercredi 7 octobre 2020 - 13:20:04

Fichier

srep40162.pdf
Publication financée par une institution

Identifiants

Collections

Citation

Fayçal Ounnas, Michel de Lorgeril, Patricia Salen, François Laporte, Luca Calani, et al.. Rye polyphenols and the metabolism of n-3 fatty acids in rats: a dose dependent fatty fish-like effect. Scientific Reports, Nature Publishing Group, 2017, 7 (1), ⟨10.1038/srep40162⟩. ⟨hal-01928613⟩

Partager

Métriques

Consultations de la notice

267

Téléchargements de fichiers

554