l-Citrulline Supports Vascular and Muscular Benefits of Exercise Training in Older Adults
Résumé
Age-associated reduction in endothelial nitric oxide (NO) synthesis contributes to the development of cardiovascular diseases and sarcopenia. l -Citrulline is a precursor of NO with the ability to improve vascular function and muscle protein synthesis. We hypothesize that vascular and muscular benefits associated with oral l -citrulline supplementation might be augmented by concomitant supplementation with exercise training in older adults.