Introduction: Self-esteem is central to human well-being, quality of life, and mental health. Therefore, it is important to propose preventive and therapeutic techniques to deal with decline in self-esteem. Different interventions have been proposed and their efficacies have been validated. However, they present certain constraints such as a cognitive and/or emotional cost, which limit some clinical applications. Method: Based on contributions from cognitive, social, and clinical psychology, we propose to test the efficacy of a new technique for self-esteem enhancement using brief lexical associations and mental visualization (six sessions of five minutes) for a stimulation of episodic and semantic self-perceptions. Results: Comparing the Lexical Association Technique to a control technique and using a double-blind pre-post design, two studies show the efficacy of this new technique on global self-esteem in two samples of students (n Study1 = 36; n Study2 = 89), as well as a sustained effect up to 5 days after the technique is stopped. Discussion: The mechanisms underlying the efficacy of this technique are discussed. Further studies are needed to precise the clinical applicability of the Lexical Association Technique on patients.