Building de novo cryo-electron microscopy structures collaboratively with citizen scientists - Université Grenoble Alpes
Article Dans Une Revue PLoS Biology Année : 2019

Building de novo cryo-electron microscopy structures collaboratively with citizen scientists

Résumé

With the rapid improvement of cryo-electron microscopy (cryo-EM) resolution, new computational tools are needed to assist and improve upon atomic model building and refinement options. This communication demonstrates that microscopists can now collaborate with the players of the computer game Foldit to generate high-quality de novo structural models. This development could greatly speed the generation of excellent cryo-EM structures when used in addition to current methods.
Fichier principal
Vignette du fichier
Khatib et al. Plos.pdf (953.88 Ko) Télécharger le fichier
Origine Fichiers éditeurs autorisés sur une archive ouverte

Dates et versions

hal-02420012 , version 1 (24-11-2020)

Identifiants

Citer

Firas Khatib, Ambroise Desfosses, Brian Koepnick, Jeff Flatten, Zoran Popović, et al.. Building de novo cryo-electron microscopy structures collaboratively with citizen scientists. PLoS Biology, 2019, 17 (11), pp.e3000472. ⟨10.1371/journal.pbio.3000472⟩. ⟨hal-02420012⟩
219 Consultations
104 Téléchargements

Altmetric

Partager

More