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Article dans une revue

Building de novo cryo-electron microscopy structures collaboratively with citizen scientists

Abstract : With the rapid improvement of cryo-electron microscopy (cryo-EM) resolution, new computational tools are needed to assist and improve upon atomic model building and refinement options. This communication demonstrates that microscopists can now collaborate with the players of the computer game Foldit to generate high-quality de novo structural models. This development could greatly speed the generation of excellent cryo-EM structures when used in addition to current methods.
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https://hal.univ-grenoble-alpes.fr/hal-02420012
Contributeur : Frank Thomas <>
Soumis le : jeudi 19 décembre 2019 - 16:41:20
Dernière modification le : mardi 6 octobre 2020 - 16:12:09

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Firas Khatib, Ambroise Desfosses, Brian Koepnick, Jeff Flatten, Zoran Popović, et al.. Building de novo cryo-electron microscopy structures collaboratively with citizen scientists. PLoS Biology, Public Library of Science, 2019, 17 (11), pp.e3000472. ⟨10.1371/journal.pbio.3000472⟩. ⟨hal-02420012⟩

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