Part I: Concepts in cell biology and examples of multiscale studies in biology 1: Introduction to cell biology, Franz Bruckert 2: A small leak will sink a great ship: HIV-host interactions, Nikolas Herold, Hans-Georg Kräusslich, Barbara Müller 3: Flower development: an integrated view, Icham Chahtane, Grégoire Denay, Julia Engelhorn, Marie Monniaux, Edwige Moyroud, Fanny Moreau, Cristel Carles, Gabrielle Tichtinsky, Chloe Zubieta, François Parcy Part II: Concepts in Physics and emerging methods 4: Thermodynamics (a reminder), Guiseppe Zaccai 5: NMR spectroscopy, from basic concepts to advanced methods, Enrico Luchinat 6: SEC-MALLS to determine protein oligomeric states, Albert Guskov, Dirk Jan Slotboom Part III: Plant development: from genes to growth 7: Mechanisms controlling time measurement in plants and their significance in natural populations, George Coupland 8: Forces in plant development, Oliver Hamant 9: Virtual plants, Christophe Godin Part IV: Forces in Biology: reshaping membranes 10: Membrane remodeling: theoretical principles, structures of protein scaffolds and forces involved, Patricia Bassereau, Winfried Weissenhorn, Michael Kozlov Part V: Conformational changes and their implications in diseases 11: Protein conformational changes, Yves Gaudin Part VI: Membrane transporters: from structure to function 12: The do's and don'ts in handling membrane proteins for structural studies, Christine Ziegler 13: Molecular simulation: a virtual microscope in the toolbox of integrated structural biology, François Dehez