Conformational Dynamics and Interactions of Membrane Proteins by Hydrogen/Deuterium Mass Spectrometry.

Eric Forest; Petr Man

doi:10.1007/978-1-4939-3637-3_17

Article dans une revue

Conformational Dynamics and Interactions of Membrane Proteins by Hydrogen/Deuterium Mass Spectrometry.

Eric Forest ¹ Petr Man ²

1 IBS - UMR 5075 - Institut de biologie structurale

2 Institute of Microbiology

Abstract : Hydrogen/deuterium exchange associated with mass spectrometry has been recently used to characterize the dynamics and the interactions of membrane proteins. Here we describe experimental workflow enabling localization of the regions involved in conformational changes or interactions.

Keywords : Conformational change Dynamics Hydrogen/deuterium exchange Interaction Mass spectrometry Membrane protein

Type de document :

Article dans une revue

Domaine :

Sciences du Vivant [q-bio] / Biochimie, Biologie Moléculaire / Biologie structurale [q-bio.BM]

Liste complète des métadonnées

https://hal.univ-grenoble-alpes.fr/hal-01431533
Contributeur : Frank Thomas <>
Soumis le : mercredi 11 janvier 2017 - 09:23:22
Dernière modification le : mercredi 14 octobre 2020 - 04:17:51