Protein mannosylation as a diagnostic and prognostic biomarker of lupus nephritis: an unusual glycan‐neoepitope in Systemic Lupus Erythematosus - Université Grenoble Alpes Accéder directement au contenu
Article Dans Une Revue Arthritis & rheumatology Année : 2021

Protein mannosylation as a diagnostic and prognostic biomarker of lupus nephritis: an unusual glycan‐neoepitope in Systemic Lupus Erythematosus

Protein mannosylation as a diagnostic and prognostic biomarker of lupus nephritis: an unusual glycan-neoepitope in Systemic Lupus Erythematosus.

Michel Thepaut
Franck Fieschi

Résumé

Changes in protein glycosylation are a hallmark of immune-mediated diseases. Glycans are master regulators of the inflammatory response being important molecules for the discrimination between "self"/"non-self". We here explored whether lupus nephritis (LN) exhibit an altered cellular glycosylation aiming to identify a unique glycosignature that characterizes LN pathogenesis.
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Dates et versions

hal-03341919 , version 1 (13-09-2021)

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Inês Alves, Beatriz Santos-Pereira, Hans Dalebout, Sofia Santos, Manuel Vicente, et al.. Protein mannosylation as a diagnostic and prognostic biomarker of lupus nephritis: an unusual glycan‐neoepitope in Systemic Lupus Erythematosus. Arthritis & rheumatology, 2021, ⟨10.1002/art.41768⟩. ⟨hal-03341919⟩
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