Multi-wavelength photo-acoustic microscopy in the frequency domain for simultaneous excitation and detection of dyes - Université Grenoble Alpes Accéder directement au contenu
Article Dans Une Revue Biomedical optics express Année : 2019

Multi-wavelength photo-acoustic microscopy in the frequency domain for simultaneous excitation and detection of dyes

Résumé

An optical-resolution photoacoustic microscope with modulated CW laser diodes allowing multi-channel imaging is presented that can be used for both imaging biological tissues and for targeted photo-dynamic therapy (PDT) varying the optical power and exposure time. The effects of this therapy are immediately monitored in order to optimize the time of irradiation. After the description of the experimental setup, in vitro and in vivo applications are presented on a synthetic sample and on the mouse ear using hemoglobin as endogenous and methylene blue as exogenous dye for imaging and PDT, respectively.
Fichier principal
Vignette du fichier
boe-10-2-932.pdf (5.1 Mo) Télécharger le fichier
Origine : Fichiers éditeurs autorisés sur une archive ouverte
Loading...

Dates et versions

hal-02001997 , version 1 (31-01-2019)

Identifiants

Citer

Olivier Hugon, Boudewijn van Der Sanden, Mehdi Inglebert, Olivier Jacquin, Chaouqi Misbah, et al.. Multi-wavelength photo-acoustic microscopy in the frequency domain for simultaneous excitation and detection of dyes. Biomedical optics express, 2019, 10 (2), pp.932. ⟨10.1364/boe.10.000932⟩. ⟨hal-02001997⟩
78 Consultations
120 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More