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Article dans une revue

Regulation of the proteome by amino acids

Abstract : Besides their main contribution as substrates for protein synthesis, amino acids as signaling molecules could exert some regulatory functions on protein synthesis and/or proteolysis that have been emphasized in a number of recent studies. Several publications have highlighted supplemental roles of those amino acids in protein metabolism as well as in immunity, heat shock response, or apoptosis processes. In this way, via their regulatory properties, selected amino acids (such as leucine, glutamine, arginine, citrulline, or methionine) directly influence the proteome. In this review, we are proposing an overview of the regulation of the proteome by amino acids in mammals.
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Contributeur : Sarah Hamant <>
Soumis le : vendredi 23 novembre 2018 - 15:17:30
Dernière modification le : mardi 28 juillet 2020 - 03:02:21

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Sandrine Bourgoin-Voillard, Arthur Goron, Michel Seve, Christophe Moinard. Regulation of the proteome by amino acids. Proteomics, Wiley-VCH Verlag, 2016, 16 (5), pp.831 - 846. ⟨10.1002/pmic.201500347⟩. ⟨hal-01933114⟩



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