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Article Dans Une Revue Journal of Clinical Medicine Année : 2023

Editorial: Kinin 2022 Meeting, Annecy, France

Résumé

The Kinin 2022 meeting took place at the Imperial Palace, Annecy, France, from 5–8 June 2022. The opening presentation by Professor Diana Karpman of Lund University focused on the interactions of the renin–angiotensin (RAS), kallikrein–kinin (KKS), and complement systems in inflammation [1]. She presented new data that bradykinin B1 receptor (B1R) antagonists reduced C5a and C5b-9 in cell lysates treated with kaolinactivated normal serum. Both C1 inhibitor (C1INH) and a B1R antagonist reduced C3 fluorescence on renal glomeruli in combined B1R/bradykinin B2 receptor (B2R) knockout mice, suggesting reduced complement activation on glomerular endothelial cells.
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hal-04464366 , version 1 (11-04-2024)

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Alvin H Schmaier, Arije Ghannam, Christian Drouet. Editorial: Kinin 2022 Meeting, Annecy, France. Journal of Clinical Medicine, 2023, Updates in Kallikrein-Kinin System, 12 (9), pp.3276. ⟨10.3390/jcm12093276⟩. ⟨hal-04464366⟩

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