The model order reduction techniques based on the multipoint projection Krylov methods have become the methods of choice to generate large macromodels of multiport RLC circuits. A well-known difficulty with such methods lies in the need for clever point selection to attain model compactness and accuracy. In this paper, we present an automatic methodology for optimizing sample point selection. This method is general, suitable for circuits obtained by the partial element equivalent circuit method coupled with an adaptive multilevel fast multipole method. Our algorithm has been validated on an industrial example to demonstrate the accuracy and robustness of the approach.