Nova tripanozomiaze humana: estudos sobre a morfolojia e o ciclo evolutivo do Schizotrypanum cruzi n. g., n. sp., ajente etiolojico de nova entidade morbida do homem, Memórias do Instituto Oswaldo Cruz, vol.1, pp.159-218, 1909. ,
The history of Chagas disease, Parasites & Vectors, vol.7, issue.1, p.317, 2014. ,
, World Health Organization, Chagas Disease (American Trypanosomiasis) Fact Sheet N ° 340, World Health Organization, 2015.
Diagnosis and management of Chagas disease and cardiomyopathy, Nature Reviews Cardiology, vol.9, issue.10, pp.576-589, 2012. ,
Indeterminate form of Chagas disease. Proposal of new diagnostic criteria and perspectives for early treatment of cardiomyopathy, Arquivos Brasileiros de Cardiologia, vol.79, issue.6, pp.623-627, 2002. ,
Chagasic cardiomyopathy, from acute to chronic: is this mediated by host susceptibility factors?, Transactions of the Royal Society of Tropical Medicine & Hygiene, vol.106, issue.9, pp.521-527, 2012. ,
Fibrosis and inflammatory cells in human chronic chagasic myocarditis: scanning electron microscopy and immunohistochemical observations, International Journal of Cardiology, vol.66, issue.2, pp.183-194, 1998. ,
TGF-? signaling and the fibrotic response, The FASEB Journal, vol.18, issue.7, pp.816-827, 2004. ,
TGF-? signal transduction, Annual Review of Biochemistry, vol.67, issue.1, pp.753-791, 1998. ,
Implication of transforming growth factor-?1 in Chagas disease myocardiopathy, The Journal of Infectious Diseases, vol.186, issue.12, pp.1823-1828, 2002. ,
Predictive value of transforming growth factor-?1 in Chagas disease: towards a biomarker surrogate of clinical outcome, Transactions of the Royal Society of Tropical Medicine & Hygiene, vol.107, issue.8, pp.518-525, 2013. ,
Proteins involved on TGF-? pathway are up-regulated during the acute phase of experimental Chagas disease, Immunobiology, vol.221, issue.5, pp.587-594, 2016. ,
SB-431542, a transforming growth factor ? inhibitor, impairs Trypanosoma cruzi infection in cardiomyocytes and parasite cycle completion, Antimicrobial Agents and Chemotherapy, vol.51, issue.8, pp.2905-2910, 2007. ,
Pharmacological inhibition of transforming growth factor ? signaling decreases infection and prevents heart damage in acute Chagas' disease, Antimicrobial Agents and Chemotherapy, vol.53, issue.11, pp.4694-4701, 2009. ,
Oral administration of GW788388, an inhibitor of transforming growth factor beta signaling, prevents heart fibrosis in Chagas disease, PLoS Neglected Tropical Diseases, vol.6, issue.6, p.1696, 2012. ,
Transforming growth factor ? gene maps to human chromosome 19 long arm and to mouse chromosome 7, Somatic Cell and Molecular Genetics, vol.12, issue.3, pp.281-288, 1986. ,
Transforming growth factor-?1 gene polymorphisms and coronary artery disease, Clinical Science, vol.95, issue.6, pp.659-667, 1998. ,
Changes to signal peptide and the level of transforming growth factor-?1 due to T869C polymorphism of TGF ?1 associated with lupus renal fibrosis, SpringerPlus, vol.3, issue.1, p.514, 2014. ,
Analysis of genetic polymorphisms in the transforming growth factor-?1 gene and the risk of Alzheimer's disease, Human Genetics, vol.106, issue.5, pp.565-569, 2000. ,
, Disease Markers
Genetic control of the circulating concentration of transforming growth factor type ?1, Human Molecular Genetics, vol.8, issue.1, pp.93-97, 1999. ,
A molecular mechanism for the differential regulation of TGF-?1 expression due to the common SNP ?509C-T (c. ?1347C > T), Human Genetics, vol.120, issue.4, pp.461-469, 2006. ,
Genotypic variation in the transforming growth factor-?1 gene: association with transforming growth factor-?1 production, fibrotic lung disease, and graft fibrosis after lung transplantation, Transplantation, vol.66, issue.8, pp.1014-1020, 1998. ,
Association of transforming growth factor-?1 gene polymorphisms with genetic susceptibility to acute myocardial infarction, The American Journal of the Medical Sciences, vol.342, issue.5, pp.365-370, 2011. ,
Association between transforming growth factor ?1 polymorphisms and left ventricle hypertrophy in essential hypertensive subjects, Molecular and Cellular Biochemistry, vol.335, issue.1-2, pp.13-17, 2010. ,
Transforming growth factor beta 1 (TGF?1) gene polymorphisms and Chagas disease susceptibility in Peruvian and Colombian patients, Cytokine, vol.45, issue.3, pp.149-153, 2009. ,
Dealing with initial inconclusive serological results for chronic Chagas disease in clinical practice, European Journal of Clinical Microbiology & Infectious Diseases, vol.31, issue.6, pp.965-974, 2012. ,
, 2nd Brazilian Consensus on Chagas Disease, vol.49, pp.3-60, 2015.
I Latin American guidelines for the diagnosis and treatment of Chagas cardiomyopathy, Arquivos Brasileiros de Cardiologia, vol.97, issue.2, pp.1-48, 2011. ,
Frequency of TGF-? and IFN-? genotype as risk factors for acute kidney injury and death in intensive care unit patients, BioMed Research International, vol.2014, 2014. ,
On estimating the relation between blood group and disease, Annals of Human Genetics, vol.19, issue.4, pp.251-253, 1955. ,
The estimation and significance of the logarithm of a ratio of frequencies, Annals of Human Genetics, vol.20, issue.4, pp.309-311, 1956. ,
Revisiting the genetic ancestry of Brazilians using autosomal AIMindels, PLoS One, vol.8, issue.9, p.75145, 2013. ,
Genetic susceptibility to chronic Chagas disease: an overview of single nucleotide polymorphisms of cytokine genes, Cytokine, vol.59, issue.2, pp.203-208, 2012. ,
Functional IL18 polymorphism and susceptibility to chronic Chagas disease, Cytokine, vol.73, issue.1, pp.79-83, 2015. ,
URL : https://hal.archives-ouvertes.fr/hal-01592692
The TGF-? pathway as an emerging target for Chagas disease therapy, Clinical Pharmacology & Therapeutics, vol.92, issue.5, pp.613-621, 2012. ,
Activation of transforming growth factor ? by Trypanosoma cruzi, Cellular Microbiology, vol.7, issue.4, pp.511-517, 2005. ,
URL : https://hal.archives-ouvertes.fr/inserm-00375793
Uptake of host cell transforming growth factor-? by Trypanosoma cruzi amastigotes in cardiomyocytes: potential role in parasite cycle completion, The American Journal of Pathology, vol.167, issue.4, pp.993-1003, 2005. ,
URL : https://hal.archives-ouvertes.fr/inserm-00207611
Regulation of Trypanosoma cruzi infections in vitro and in vivo by transforming growth factor beta (TGF-beta), The Journal of Experimental Medicine, vol.174, issue.3, pp.539-545, 1991. ,
The pattern of myocardial fibrosis in chronic Chagas' heart disease, International Journal of Cardiology, vol.30, issue.3, pp.335-340, 1991. ,
Immunoneuroendocrine alterations in patients with progressive forms of chronic Chagas disease, Journal of Neuroimmunology, vol.235, issue.1-2, pp.84-90, 2011. ,
Circulating serum markers and QRS scar score in Chagas cardiomyopathy, The American Journal of Tropical Medicine and Hygiene, vol.92, issue.1, pp.39-44, 2015. ,
DOI : 10.4269/ajtmh.14-0246
URL : http://www.ajtmh.org/deliver/fulltext/14761645/92/1/39.pdf?itemId=/content/journals/10.4269/ajtmh.14-0246&mimeType=pdf&containerItemId=content/journals/14761645
Growth factors in the myocardium of patients with chronic chagasic cardiomyopathy, Revista da Sociedade Brasileira de Medicina Tropical, vol.33, issue.6, pp.509-518, 2000. ,
Myocardial gene expression of T-bet, GATA-3, Ror-?t, FoxP3, and hallmark cytokines in chronic Chagas disease cardiomyopathy: an essentially unopposed T H 1-type response, Mediators of Inflammation, vol.2014, 2014. ,
Invasive and noninvasive correlations of B-type natriuretic peptide in patients with heart failure due to Chagas cardiomyopathy, Congestive Heart Failure, vol.14, issue.3, pp.121-126, 2008. ,
Admixture in Latin America: geographic structure, phenotypic diversity and self-perception of ancestry based on 7,342 individuals, PLoS Genetics, vol.10, issue.9, p.1004572, 2014. ,
Left atrial and left ventricular diastolic function in chronic Chagas disease, Journal of the American Society of Echocardiography, vol.26, issue.12, pp.1424-1433, 2013. ,
DOI : 10.1016/j.echo.2013.08.018
Immunoregulatory networks in human Chagas disease, Parasite Immunology, vol.36, issue.8, pp.377-387, 2014. ,
DOI : 10.1111/pim.12107
URL : http://europepmc.org/articles/pmc4143493?pdf=render
Dual role for transforming growth factor ?-dependent signaling in Trypanosoma cruzi infection of mammalian cells, Infection and Immunity, vol.68, issue.4, pp.2077-2081, 2000. ,
, Disease Markers
In situ expression of regulatory cytokines by heart inflammatory cells in Chagas' disease patients with heart failure, Clinical and Developmental Immunology, vol.2012, 2012. ,
TGF-? polymorphisms are a risk factor for Chagas disease, 5a Edição do Ciclo de Palestras Carlos Chagas ,
DOI : 10.1155/2018/4579198
URL : https://hal.archives-ouvertes.fr/hal-02010997