Structure of influenza virus RNP. I. Influenza virus nucleoprotein melts secondary structure in panhandle RNA and exposes the bases to the solvent, Embo J, vol.13, pp.3158-3165, 1994. ,
Structure of the RNA inside the vesicular stomatitis virus nucleocapsid, Rna, vol.6, pp.270-281, 2000. ,
Role of the nucleocapsid protein in regulating vesicular stomatitis virus RNA synthesis, Cell, vol.41, pp.259-267, 1985. ,
RNA polymerase of influenza virus: role of NP in RNA chain elongation, J Biochem, vol.104, pp.1021-1026, 1988. ,
Nucleoproteins and nucleocapsids of negative-strand RNA viruses, Curr Opin Microbiol, vol.14, pp.504-510, 2011. ,
Complex formation with vesicular stomatitis virus phosphoprotein NS prevents binding of nucleocapsid protein N to nonspecific RNA, J Virol, vol.62, pp.2658-2664, 1988. ,
An N-terminal domain of the Sendai paramyxovirus P protein acts as a chaperone for the NP protein during the nascent chain assembly step of genome replication, J Virol, vol.69, pp.849-855, 1995. ,
Rabies virus chaperone: identification of the phosphoprotein peptide that keeps nucleoprotein soluble and free from non-specific RNA, Virology, vol.349, pp.422-429, 2006. ,
URL : https://hal.archives-ouvertes.fr/hal-02668639
Structure of the vesicular stomatitis virus N(0)-P complex, PLoS Pathog, vol.7, p.1002248, 2011. ,
Structure of the Rift Valley fever virus nucleocapsid protein reveals another architecture for RNA encapsidation, Proc Natl Acad Sci U S A, vol.107, pp.11769-11774, 2010. ,
The hexamer structure of Rift Valley fever virus nucleoprotein suggests a mechanism for its assembly into ribonucleoprotein complexes, PLoS Pathog, vol.7, p.1002030, 2011. ,
Phleboviruses encapsidate their genomes by sequestering RNA bases, Proc Natl Acad Sci U S A, vol.109, pp.19208-19213, 2012. ,
Cap binding and immune evasion revealed by Lassa nucleoprotein structure, Nature, vol.468, pp.779-783, 2010. ,
Structure of the Lassa virus nucleoprotein reveals a dsRNA-specific 39 to 59 exonuclease activity essential for immune suppression, Proc Natl Acad Sci U S A, vol.108, pp.2396-2401, 2011. ,
Crystal structure of the Lassa virus nucleoprotein-RNA complex reveals a gating mechanism for RNA binding, Proc Natl Acad Sci U S A, vol.108, pp.19365-19370, 2011. ,
The mechanism by which influenza A virus nucleoprotein forms oligomers and binds RNA, Nature, vol.444, pp.1078-1082, 2006. ,
Structure of the influenza virus A H5N1 nucleoprotein: implications for RNA binding, oligomerization, and vaccine design, Faseb J, vol.22, pp.3638-3647, 2008. ,
Structural basis for RNA binding and homo-oligomer formation by influenza B virus nucleoprotein, J Virol, vol.86, pp.6758-6767, 2012. ,
Structure of influenza virus ribonucleoprotein particles. II. Purified RNA-free influenza virus ribonucleoprotein forms structures that are indistinguishable from the intact influenza virus ribonucleoprotein particles, J Gen Virol, vol.76, pp.1009-1014, 1995. ,
Oligomerization paths of the nucleoprotein of influenza A virus, Biochimie, vol.94, pp.776-785, 2012. ,
URL : https://hal.archives-ouvertes.fr/hal-02650463
Biochemical and structural evidence in support of a coherent model for the formation of the double-helical influenza a virus ribonucleoprotein, MBio, vol.4, pp.467-00412, 2013. ,
Oligomerization of the influenza virus nucleoprotein: identification of positive and negative sequence elements, Virology, vol.260, pp.190-200, 1999. ,
Functional analysis of the influenza virus H5N1 nucleoprotein tail loop reveals amino acids that are crucial for oligomerization and ribonucleoprotein activities, J Virol, vol.84, pp.7337-7345, 2010. ,
Human importin alpha and RNA do not compete for binding to influenza A virus nucleoprotein, Virology, vol.409, pp.84-90, 2011. ,
The structure of a biologically active influenza virus ribonucleoprotein complex, PLoS Pathog, vol.5, p.1000491, 2009. ,
E339?R416 salt bridge of nucleoprotein as a feasible target for influenza virus inhibitors, Proc Natl Acad Sci U S A, vol.108, pp.16515-16520, 2011. ,
Phosphorylation of influenza virus nucleoprotein in vivo, J Gen Virol, vol.57, pp.185-190, 1981. ,
Differential phosphorylation of the nucleoprotein of influenza A viruses, J Gen Virol, vol.70, pp.2421-2431, 1989. ,
Phosphorylation of the nucleoprotein of an avian influenza virus, J Gen Virol, vol.60, pp.295-305, 1982. ,
Structure of the ribonucleoprotein of influenza virus, J Virol, vol.10, pp.795-800, 1972. ,
Ultrastructural and functional analyses of recombinant influenza virus ribonucleoproteins suggest dimerization of nucleoprotein during virus amplification, J Virol, vol.74, pp.156-163, 2000. ,
Mapping the phosphoproteome of influenza a and B viruses by mass spectrometry, PLoS Pathog, vol.8, p.1002993, 2012. ,
The Structure of Native Influenza Virion Ribonucleoproteins, Science, vol.338, pp.1634-1637, 2012. ,
Organization of the Influenza Virus Replication Machinery, Science, vol.338, pp.1631-1634, 2012. ,
The influenza virus panhandle is involved in the initiation of transcription, J Virol, vol.68, pp.4092-4096, 1994. ,
Sequence-specific binding of the influenza virus RNA polymerase to sequences located at the 59 ends of the viral RNAs, J Virol, vol.68, pp.5108-5116, 1994. ,
Recombinant influenza virus polymerase: requirement of both 59 and 39 viral ends for endonuclease activity, J Virol, vol.68, pp.1509-1515, 1994. ,
Differential activation of the influenza virus polymerase via template RNA binding, J Virol, vol.69, pp.3995-3999, 1995. ,
Roles of the influenza virus polymerase and nucleoprotein in forming a functional RNP structure, Embo J, vol.16, pp.1248-1257, 1997. ,
Genetic trans-complementation establishes a new model for influenza virus RNA transcription and replication, PLoS Pathog, vol.5, p.1000462, 2009. ,
The influenza virus RNA synthesis machine: advances in its structure and function, RNA Biol, vol.8, pp.207-215, 2011. ,
Sequence in the influenza A virus nucleoprotein required for viral polymerase binding and RNA synthesis, J Virol, vol.86, pp.7292-7297, 2012. ,
Molecular dynamics studies of the nucleoprotein of influenza A virus: role of the protein flexibility in RNA binding, PLoS One, vol.7, p.30038, 2012. ,
URL : https://hal.archives-ouvertes.fr/hal-02647086
Identification of influenza A nucleoprotein as an antiviral target, Nat Biotechnol, vol.28, pp.600-605, 2010. ,
High-throughput identification of compounds targeting influenza RNA-dependent RNA polymerase activity, Proc Natl Acad Sci U S A, vol.107, pp.19151-19156, 2010. ,
Inhibition of influenza virus replication via small molecules that induce the formation of higher-order nucleoprotein oligomers, Proc Natl Acad Sci U S A, vol.108, pp.15366-15371, 2011. ,
Automatic Processing of Rotation Diffraction Data from Crystals of Initially Unknown Symmetry and Cell Constants, Journal of Applied Crystallography, vol.26, pp.795-800, 1993. ,
Integration, scaling, space-group assignment and postrefinement, Acta Crystallogr D Biol Crystallogr, vol.66, pp.133-144, 2010. ,
, The CCP4 suite: programs for protein crystallography, Collaborative Computational Project n, vol.50, pp.760-763, 1994.
The PyMOL Molecular Graphics System, 2002. ,
Non-specific' binding. The problem, and a solution, Biochem J, vol.228, pp.269-272, 1985. ,
Rapid grid-based construction of the molecular surface and the use of induced surface charge to calculate reaction field energies: applications to the molecular systems and geometric objects, J Comput Chem, vol.23, pp.128-137, 2002. ,