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Journal Articles Structure Year : 2014

A small switch has a large effect on autophagy.

Abstract

Atg8 family proteins and Atg13 are important regulators of autophagy. In this issue of Structure, Suzuki and colleagues describe crystal structures of light chain 3 (LC3; Atg8) in complex with the Atg13 LC3 interacting region (LIR) motif and identify a subtle switch of side chain conformation regulating the LC3-LIR interaction and autophagosome formation in vivo.
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Dates and versions

hal-01102535 , version 1 (13-01-2015)

Identifiers

  • HAL Id : hal-01102535 , version 1
  • PUBMED : 24411573

Cite

Winfried Weissenhorn, Marie-Odile Fauvarque. A small switch has a large effect on autophagy.. Structure, 2014, 22, pp.1-2. ⟨hal-01102535⟩
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