Gram-type differentiation of bacteria with 2D hollow photonic crystal cavities

Fast and label-free techniques to analyze viruses and bacteria are of crucial interest in biological and bio-medical applications. For this purpose, optofluidic systems based on the integration of photonic structures with microfluidic layers were shown to be promising tools for biological analysis, thanks to their small footprint and to their ability to manipulate objects using low powers. In this letter, we report on the optical trapping of living bacteria in a 2D silicon hollow photonic crystal cavity. This structure allows for the Gram-type differentiation of bacteria at the single cell scale, in a fast, label-free, and non-destructive way.

Domaines

Biotechnologies Optique / photonique Micro et nanotechnologies/Microélectronique

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1.5037849.pdf (1.94 Mo)

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https://cea.hal.science/cea-01988778

Soumis le : mardi 22 janvier 2019-09:19:10

Dernière modification le : mardi 3 septembre 2024-11:16:05

Dates et versions

cea-01988778 , version 1 (22-01-2019)

Identifiants

HAL Id : cea-01988778 , version 1
DOI : 10.1063/1.5037849

Citer

R. Therisod, M. Tardif, P. R. Marcoux, E. Picard, J.-B. Jager, et al.. Gram-type differentiation of bacteria with 2D hollow photonic crystal cavities. Applied Physics Letters, 2018, 113 (11), pp.111101. ⟨10.1063/1.5037849⟩. ⟨cea-01988778⟩

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