Backbone resonance assignments of the micro-RNA precursor binding region of human TRBP

Abstract : TAR-RNA binding protein (TRBP) is a multidomain human protein involved in micro-RNA (miRNA) biogenesis. TRBP is a component of both the Dicer complex, which processes precursor miRNAs, and the RNA-induced silencing complex-loading complex. In addition, TRBP is implicated in the human immunodeficiency virus replication cycle and interferon-protein kinase R activity. TRBP contains 3 double-stranded RNA binding domains the first two of which have been shown to interact with miRNA precursors. Here we present the backbone resonance assignments and secondary structure of residues 19-228 of human TRBP2.
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Biomolecular NMR Assignments, Springer, 2013, 7 (2), pp.229-233. 〈10.1007/s12104-012-9416-8〉
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Soumis le : jeudi 26 mai 2016 - 08:27:50
Dernière modification le : lundi 19 février 2018 - 14:34:03

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Matthieu Benoit, Michael J Plevin. Backbone resonance assignments of the micro-RNA precursor binding region of human TRBP. Biomolecular NMR Assignments, Springer, 2013, 7 (2), pp.229-233. 〈10.1007/s12104-012-9416-8〉. 〈hal-01321560〉

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