Essential and supporting host cell factors for HIV-1 budding.

Abstract : HIV-1 employs its structural proteins to orchestrate assembly and budding at the plasma membrane of host cells. The Gag polyprotein is sufficient to form virus-like particles in the absence of other viral proteins and provides a platform to interact with numerous cellular factors that regulate Gag trafficking to the site of assembly and budding. Notably endosomal sorting complexes required for transport have attained much attention over the last decade because of their essential role in virion release. Here we review recent advances in understanding the role of host cell factors recruited by Gag during HIV-1 assembly and budding.
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Article dans une revue
Future Microbiology, Future Medicine, 2011, 6 (10), pp.1159-70
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http://hal.univ-grenoble-alpes.fr/hal-01243642
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Soumis le : mardi 15 décembre 2015 - 11:30:43
Dernière modification le : lundi 19 février 2018 - 14:34:03

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  • HAL Id : hal-01243642, version 1
  • PUBMED : 22004035

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Aurelien Dordor, Emilie Poudevigne, Heinrich Göttlinger, Winfried Weissenhorn. Essential and supporting host cell factors for HIV-1 budding.. Future Microbiology, Future Medicine, 2011, 6 (10), pp.1159-70. 〈hal-01243642〉

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