Adult patients hospitalized for measles in France, in the 21st century.

Abstract : An epidemic of measles broke out in France in 2008. We designed a retrospective study focusing on adults hospitalized for measles in 2010/2011. A case was any patient aged more than 15 years, hospitalized (September 2010 to September 2011) with a typical rash or a biological diagnosis. Data was collected with standardized questionnaires in participating hospitals. Four hundred and sixty cases were reported: sex-ratio (M/F) = 0.93, median age 26 years (σ = 8.8). Twenty-nine cases were severe (6.5%), 27 of which hospitalized in an ICU. Three hundred and twelve (68%) cases had elevated serum transaminases (EST), 155 (34%) cases had pneumonia, 34 (7%) cases had elevated serum creatinine (ESC), four (0.9%) cases had elevated serum amylase and lipase (ESAL), and three (0.7%) cases had neurological symptoms. One hundred and four (23%) patients presented simultaneously with EST and pneumonia. One patient presenting with severe pneumonia died (0.2%). One hundred and ten (24%) patients received antibiotics during a median seven days. Measles can present as various syndromes in adults and be responsible for a high burden during outbreaks. The immediate outcome is favorable in most patients. Long-term outcome needs further investigations to identify possible late complications.
Type de document :
Article dans une revue
Médecine et Maladies Infectieuses, Elsevier Masson, 2013, 43 (10), pp.410-6
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http://hal.univ-grenoble-alpes.fr/hal-01243592
Contributeur : Frank Thomas <>
Soumis le : mardi 15 décembre 2015 - 11:00:38
Dernière modification le : jeudi 11 janvier 2018 - 06:26:04

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  • HAL Id : hal-01243592, version 1
  • PUBMED : 24050842

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J P Stahl, D Salmon, F Bruneel, E Caumes, F Freymuth, et al.. Adult patients hospitalized for measles in France, in the 21st century.. Médecine et Maladies Infectieuses, Elsevier Masson, 2013, 43 (10), pp.410-6. 〈hal-01243592〉

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