Interaction between Bacillus subtilis YsxC and ribosomes (or rRNAs).

Abstract : YsxC is an essential P-loop GTPase, that binds to the 50S ribosomal subunit, and is required for the proper assembly of the ribosome. The aim of this study was to characterize YsxC ribosome interactions. The stoichiometry of YsxC ribosome subunit complex was evaluated. We showed that YsxC binding to the 50S ribosomal subunit is not affected by GTP, but in the presence of GDP the stoichiometry of YsxC-ribosome is decreased. YsxC GTPase activity was stimulated upon 50S ribosomal subunit binding. In addition, it is shown for the first time that YsxC binds both 16S and 23S ribosomal RNAs.
Type de document :
Article dans une revue
FEBS Letters, Wiley, 2015, 589 (9), pp.1026-32
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Soumis le : mercredi 10 juin 2015 - 11:11:37
Dernière modification le : mercredi 25 juillet 2018 - 10:52:02


  • HAL Id : hal-01162332, version 1
  • PUBMED : 25771857



Catherine Wicker-Planquart, Jean-Michel Jault. Interaction between Bacillus subtilis YsxC and ribosomes (or rRNAs).. FEBS Letters, Wiley, 2015, 589 (9), pp.1026-32. 〈hal-01162332〉



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