Semi-Conductor Oxides for Electronic Detection of Biological Molecules
Résumé
Detection and quantification of biological species are critical to many areas of health care and life science. A method using the variation of the electrical properties as a function of charged bio-molecules grafting onto a sensitive substrate processed as a semi-conductor oxide thin film is presented. It is shown that a pure and doped SnO(2) thin film can be used as the sensitive element. The sensitivity evolution as a function of the film microstructure, composition and resistivity is studied. It is shown that dense and conductive films are less efficient. The relation between the microstructure and the sensitivity is discussed.