Since the PAMELA results on the anomalously high positron fraction and the lack of antiproton excess in our Galaxy, there has been a tremendous number of studies advocating new types of dark matter, with larger couplings to electrons than to quarks. Is this feature a bad sign for the dark matter detection prospects at LHC? Since the WIMP couplings to quarks are constrained by PAMELA, the question of the production of dark matter (and heavy associated coloured states) at LHC definitely arises. Here we show that, despite the agreement between the PAMELA antiproton measurements and the expected astrophysical secondary background, the WIMP couplings to heavy quarks can actually be larger than the strong coupling constant. Thus PAMELA pbar/p measurements are not really challenging dark matter models. In addition, large values of the WIMP coupling to quarks suggest that heavy couloured states might be produced significantly in quark-quark collisions. We therefore investigate if this is an interesting channel to study at LHC. Finally, our analysis delineates the region of parameter space which both saturates the limits from PAMELA pbar/p measurements and jeopardizes the conventional scenario for WIMP thermal decoupling in the early universe.